Doktoranden

Böth, Alexander

M. Sc., Doktorand (Seit Juli 2019)
(Ruthenium based Hydrogenation Catalysis)

Raum: CRC 2010
Tel.: (089) 289 54203
E-Mail: alex.boeth@tum.de

Transfer hydrogenation (TH) reactions utilise hydrogen containing molecules as donors to catalytically transfer hydrogen onto other organic compounds with good activities and high adjustability. This is one of the most commonly used methods for the transformation of aldehydes and ketones to alcohols and often finds application in fine-chemical or pharmaceutical production. In my research, I focus on abnormally coordinated N-heterocyclic carbene (aNHC) ruthenium complexes. Based on our recent discovery of a highly active ruthenium catalyst, my goal is the further optimisation of this type of catalyst system and the investigation of further potential catalytic applications of ruthenium catalysts.

Büchele, Yogi

M. Sc., Doktorand (Seit Dezember 2021)
(Development of new tetra-dentate NHC ligand systems for medicinal chemistry and oxidation catalysis)

Raum CRC 4008
Tel: (089) 289 54112
Email yogi.buechele@tum.de

My research focuses on the synthesis of new tetra-dentate-NHC ligand systems with modified electronic properties for medicinal chemistry and oxidation catalysis. In addition, my work includes the synthesis and characterization of several transition-metal compounds (group 10/11) bearing the newly developed NHC ligands as well as the investigation of their application in medicinal chemistry and oxidation catalysis.

Dietl, Nicole

M. Sc., Doktorandin (Seit September 2020)
(Medicinal Chemistry)

Raum: CRC 4008
Tel.: (089) 289 54113
E-Mail: nicole.dietl@tum.de

Due to promising antiproliferative properties of various gold(I) N-heterocyclic carbenes (NHCs) my research focuses on modifications with selectivity-enhancing biomolecules. Through these, selectivity issues of common metal complexes like cisplatin against malignant cells might be reduced. My research involves the synthesis, characterization and preliminary in-vitro studies.

Imhof, Alexander

M. Sc., Doktorand (Seit Januar 2020)
(Industrial Project)

Raum: CRC 4006
Tel.: (089) 289 54111
E-mail: alexander.imhof@tum.de

Qin, Shaoheng

M. Sc., Doktorand (Seit Juni 2021)
(Photochemistry)

Raum: CRC 4008
Tel.: (089) 289 54112
E-Mail: ge42quy@mytum.de

A visible light-induced intramolecular α-alkenylation which proceeded via metal-free dehydrohalogenative C(sp2)-C(sp2) coupling reaction, yielding diffferent rings. The concepts of photoinduced metal-free C(sp2)-C(sp2) coupling and the ring synthesis are, according to our knowledge of organic chemistry, highly valuable. The significance of building macrocycles is certain because it provides route to accessing functionalized materials. Strategies of building medium sized rings are rewarding concerning ring strain, therefore the project that I will be doing is to further study the substrate scope of eight membered rings formation. My research involves the synthesis, characterization and detailed mechanistic studies of the macrocycles and eight membered rings.

List of Publication:
G. Pan, S. Qin, D. Xu, F. E. Kühn, H. Guo, Org. Lett. 2021, 23, 2959–2963.

Richter, Leon

M. Sc., Doktorand (Seit August 2021)
(Medicinal Chemistry)

Raum: CRC 4008
Tel.: (089) 289 54112
E-Mail: leon.richter@tum.de

1,2,3-Triazolylidenes are very versatile ligands in transition-metal coordination chemistry due to their relatively simple preparation and modification via click chemistry. My research includes the synthesis of several transition-metal compounds with these ligands, the functionalisation with targeting ligands/vectors and the medicinal applications of the corresponding Au(I)-complexes in chemotherapy.

Cell studies are conducted within our cooperation partnerships.

Sauer, Michael

M. Sc., Doktorand (Seit Mai 2020)
(Wacker Project)

Raum: CRC 2010
Tel.: (089) 289 54203
E-Mail: m.sauer@tum.de

Due to their unique properties, silicones are of great industrial interest. My research focuses on Pt-catalyzed hydrosilylation, where Karstedt’s catalyst and Markó’s catalyst are used as benchmark for catalytic activity and selectivity, respectively. A major problem in silicone chemistry is the irretrievable loss of Pt, as the catalyst remains in cured products. Improvement of the stability and activity of the catalyst lowers the necessary amount of Pt and could possibly avoid yellowing of silicones, which is due to Pt-nanoparticle formation.

Schlachta, Tim

M. Sc., Doktorand (Seit Februar 2021)
(Synthesis and Characterization of Iron N-Heterocyclic Carbene Complexes for C–H Oxidation)

Raum: CRC 4006
Tel.: (089) 289 54111
E-Mail: tim.schlachta@tum.de

In nature, the nonheme iron metalloenzyme methane monooxygenase is selectively catalyzing the challenging C–H oxidation reaction of inert methane to methanol. Aspired to mimic this reactivity together with the advantages of artificial catalysts, several nonheme iron complexes have been synthesized and applied in C–H oxidation reactions. However, so far, these mimics do not achieve the activity, selectivity, and stability of their model in nature.

The aim of my doctoral thesis is the synthesis, characterization and optimization of new iron complexes bearing N-heterocyclic carbenes (NHCs) for the C–H oxidation of aliphatic and aromatic hydrocarbons.

List of Publication:
[1] T. P. Schlachta, J. F. Schlagintweit, M. R. Anneser, E.-M. H.J. Esslinger, M. Muhr, S. Haslinger, F. E.Kühn,  Inorg. ChimActa 2021518, 120228.
[2] F. Dyckhoff,  J. F. Schlagintweit,  M. A. Bernd,  C. H. G. Jakob,  T. P. Schlachta, B. J. Hofmann, R. M. Reich, F. E. Kühn, Catal. Sci. Technol2021, 11, 795-799.
[3] T. P. Schlachta,   M. R. Anneser,   J. F. Schlagintweit,   C. H. G. Jakob,   C. Hintermeier,   A. D. Böth,   S. Haslinger,   R. M. Reich, F. E. Kühn, Chem. Commun. 2021, 57, 6644-6647.

 

Zámbó, Greta

M. Sc., Doktorandin (Seit Dezember 2020)
(Iron-NHC Complexes in Catalysis)

Raum: CRC 2010
Tel.: (089) 289 54203
E-Mail: greta.zambo@tum.de

Oxidative catalysis of hydrocarbons often traces back to expensive or toxic noble metals. Iron as the most abundant transition metal in earth’s crust is a promising candidate to replace such metals in their application due to its low price, low toxicity and environmental benignity. The unique properties of N-heterocyclic carbenes (NHC) provide a highly flexible ligand system for transition metal complexes, allowing for simple modification of steric and electronic parameters. My research focuses on the synthesis and characterization of cyclic and acyclic normal and mesoionic tetradentate NHC iron complexes and their application in epoxidation as well as in the challenging C–H activation catalysis.