2024   2023   2022   2021   2020   2019   2018   2017   2016   2015   2014   2013  bis 2012  




Walker, E, Heieck, K & Brück, T. Kleine Ursache, große Wirkung – den springenden DNA-Sequenzen auf der Spur. Biospektrum 30, 117–119 (2024)

Koch M, Paper M, Brück TB, Nilges T. Rare earth element stripping from kaolin sands via mild acid treatment. Asia-Pac J Chem Eng. 2024;19:e3018

Koruyucu A, Schädler T, Gniffke A, Mundt K, Krippendorf S, Urban P, Blums K, Halim B, Brück T, Weuster-Botz D. Energy-Efficient Production of Microchloropsis salina Biomass with High CO2 Fixation Yield in Open Thin-Layer Cascade Photobioreactors. Processes 2024, 12, 1303.

Keil L, Qoura F M, Breitsameter J M, Rieger B, Garbe D, Brück T B. Evaluation of Chemical and Physical Triggers for Enhanced Photosynthetic Glycerol Production in Different Dunaliella Isolates. Microorganisms 2024, 12, 1318.

Bandookwala M, Prem S A, Kollmannsberger K L, Zavrel M, Garbe D, Brück T. Immobilization study of a monomeric oleate hydratase from Rhodococcus erythropolis. Biotechnology and Bioprocess Engineering,


Koch M, Paper M, Brück TB and Nilges T. Rare earth element stripping from kaolin sands via mild acid treatment; Asia-Pacific Journal of Chemical Engineering. 2023;

Paper M, Jung P, Koch M, Lakatos M, Nilges T and Brück TB. Stripped: contribution of cyanobacterial extracellular polymeric substances to the adsorption of rare earth elements from aqueous solutions; Frontiers in Bioengineering and Biotechnology. 2023; 11.

Engelhart-Straub S, Haack M, Awad D, Brueck T, Mehlmer N. Optimization of Rhodococcus erythropolis JCM3201T nutrient media to improve biomass, lipid, and carotenoid yield using response surface methodology. Microorganisms 2023, 11(9), 2147,

Keil L, Mehlmer N, Cavelius P, Garbe D, Haack M, Ritz M, Awad D, Brück T. The Time-Resolved Salt Stress Response of Dunaliella tertiolecta - A Comprehensive System Biology Perspective. Int. J. Mol. Sci. 2023, 24(20), 15374;

Ahmad N, Ritz M, Calchera A, Otte J, Schmitt I, Brück T, Mehlmer N. Biosynthetic gene cluster synteny: Orthologous polyketide synthases in Hypogymnia physodes, Hypogymnia tubulosa, and Parmelia sulcata., MicrobiologyOpen 2023;12:e1386.

Stellner NI, Rerop ZS, Mehlmer N, Masri M, Ringel M, Brück TB. Expanding the genetic toolbox for Cutaneotrichosporon oleaginosus employing newly identified promoters and a novel antibiotic resistance marker., BMC Biotechnol 23, 40 (2023).

Prem SA, Haack M, Melcher F, Ringel M, Garbe D, Brück T. Two Cascade Reactions with Oleate Hydratases for the Sustainable Biosynthesis of Fatty Acid-Derived Fine Chemicals., Catalysts 2023, 13(9), 1236;

Arnold ND, Garbe D, Brück TB. Proteomic and Transcriptomic Analyses to Decipher the Chitinolytic Response of Jeongeupia spp., Mar. Drugs 2023, 21(8), 448;

Melcher F, Vogelsang F, Haack M, Masri M, Ringel M, Roth A, Garbe D, Brück T. Lipase-mediated plant oil hydrolysis - Towards a quantitative glycerol recovery for the synthesis of pure allyl alcohol and acrylonitrile, European Journal of Lipid Science and Technology 2023,

Arnold ND, Garbe D, Brück TB. Isolation, biochemical characterization, and genome sequencing of two high-quality genomes of a novel chitinolytic Jeongeupia species. MicrobiologyOpen. 2023;12:e1372.,

Pilz M, Cavelius P, Qoura F, Awad D, Brück T. Lipopeptides development in cosmetics and pharmaceutical applications: A comprehensive review, Biotechnology Adavances 2023,

Heffernan D, Pilz M, Klein M, Haack M, Race AM, Brück T, Qoura, F, Strittmatter N. Screening of volatile organic compounds (VOCs) from liquid fungal cultures using ambient mass spectrometry, Analytical and Bioanalytical Chemistry 2023,

Heieck K, Brück T. Localization of Insertion Sequences in Plasmids for L-Cysteine Production in E. coli, Genes 2023, 14, 1317.

Ritz M, Ahmad N, Brück T, Mehlmer N, Differential RNA-Seq Analysis Predicts Genes Related to Terpene Tailoring in Caryopteris × clandonensis, Plants 2023, 12(12), 2305;

Stellner N. I. , Rerop Z. S., Kyselka J, Alishevich K, Beneš R , Filip V, Celik G, Haack M, Ringel M, Masri M and Brück T, Value-Added Squalene in Single-Cell Oil Produced with Cutaneotrichosporon oleaginosus for Food Applications, JAFC, 2023,

Prem S A, Helmer C P O, Loll B, Garbe D, Brück T. Expanding the Portfolio by a Novel Monomeric Oleate Hydratase from Pediococcus parvulus. ChemCatChem 2023, e202300478.

Ahmad, N, Ritz, M, Calchera, A, Otte, J, Schmitt, I, Brueck, T, Mehlmer, N. Biosynthetic Potential of Hypogymnia Holobionts: Insights into Secondary Metabolite Pathways. J. Fungi 2023, 9, 546.

Nathaniel J. Berger, Mahmoud A. Masri, Thomas Brück, Daniel Garbe, Christoph Pfeifer, and Johannes Lindorfer. Utilizing a CHP Power Plant’s Energy and CO2 Emissions for the Manufacture of Affordable and Carbon Neutral Algae Bioplastic for Re-Useable Packaging. Industrial & Engineering Chemistry Research.

Babak Pakbin, Samaneh Allahyari, Shaghayegh Pishkhan Dibazar, Leila Zolghadr, Neda Karami Chermahini, Wolfram Manuel Brück, Thomas B. Brück, and Razzagh Mahmoudi. Effects of Probiotic Saccharomyces boulardii Supernatant on Viability, Nano-Mechanical Properties of Cytoplasmic Membrane and Pro-Inflammatory Gene Expression in Human Gastric Cancer AGS Cells. MDPI Molecular Science.

Cavelius P, Engelhart-Straub S, Mehlmer N, Lercher J, Awad D, Brück T. The potential of biofuels from first to fourth generation. PLoS Biol 21(3): e3002063.

Koruyucu A, Blums K, Peest T, Schmack-Rauscher L, Brück T, Weuster-Botz D. High-Cell-Density Yeast Oil Production with Diluted Substrates Imitating Microalgae Hydrolysate Using a Membrane Bioreactor. Energies 2023, 16(4), 1757

Shaigani P, Fuchs T, Graban P, Prem S, Haack M, Masri M, Mehlmer N, Brück T. Mastering targeted genome engineering of GC-rich oleaginous yeast for tailored plant oil alternatives for the food and chemical sector. Microb Cell Fact 22, 25 (2023).

Paper M, Koch M, Jung P, Lakatos M, Nilges T and Brück TB. Rare earths stick to rare cyanobacteria: Future potential for bioremediation and recovery of rare earth elements; Frontiers in Bioengineering and Biotechnology. 2023; 11.

Rerop, ZS, Stellner, NI, Graban, P, Haack, M, Mehlmer, N, Masri, M, Brück, TB. Bioconversion of a Lignocellulosic Hydrolysate to Single Cell Oil for Biofuel Production in a Cost-Efficient Fermentation Process. Fermentation 2023, 9, 189.

Cavelius P, Engelhart-Straub S, Biewald A, Haack M, Awad D, Brück T, Mehlmer N. Adaptation of Proteome and Metabolism in Different Haplotypes of Rhodosporidium toruloides during Cu(I) and Cu(II) Stress. Microorganisms 2023, 11(3), 553;

Heieck, K., Arnold, N.D. & Brück, T.B. Metabolic stress constrains microbial L-cysteine production in Escherichia coli by accelerating transposition through mobile genetic elements. Microb Cell Fact 22, 10 (2023).

Ritz M, Ahmad N, Brueck T, Mehlmer N. Comparative Genome-Wide Analysis of Two Caryopteris x Clandonensis Cultivars: Insights on the Biosynthesis of Volatile Terpenoids. Plants. 2023; 12(3):632.

Pakbin B, Brück WM, Brück TB. Molecular Mechanisms of Shigella Pathogenesis; Recent Advances. International Journal of Molecular Sciences. 2023; 24(3):2448.


Bayaraa T, Lonhienne T, Sutiono A, Melse O, Brück TB, Marcellin E, Bernhardt PV, Boden M, Harmer JR, Sieber V, Guddat LW, Schenk G. (2022) Structural and Functional Insight into the Mechanism of the Fe-S Cluster-Dependent Dehydratase from Paralcaligenes ureilyticus., Chemistry A European Journal,

Bessadok B, Jaouadi B, Brück T, Santulli A, Messina CM, Sadok S. (2022) Molecular Identification and Biochemical Characterization of Novel Marine Yeast Strains with Potential Application in Industrial Biotechnology, Fermentation,

Pakbin B, Brück WM, Brück TB, Allahyari S, Tamai IA. (2022) A quantitative prevalence of Escherichia coli O157 in different food samples using real-time qPCR method, Food Science & Nutrition,

Kleigrewe K, Haack M, Baudin M, Ménabréaz T, Crovadore J, Masri M, Beyrer M, Andlauer W, Lefort F, Dawid C, Brück T, Brück WM. (2022) Dietary modulation of the human gut microbiome and metabolome with flaxseed preparations, Bioactives,

Engelhart-Straub S, Cavelius P, Hölzl F, Haack M, Awad D, Brück T, Mehlmer N. (2022) Effects of Light on Growth and Metabolism of Rhodococcus erythropolis, Microorganisms, doi:10.3390/microorganisms10081680

Lv Y, Zheng S, Goldenzweig A, Liu F, Gao Y, Yang X, Kandale A, McGeary RP, Williams S, Kobe B, Schembri M, Landsberg M, Wu B, Brück TB, Sieber V, Boden M, Rao Z, Fleishman SJ, Schenk G, Guddat LW. (2022) Enhancing the thermal and kinetic stability of ketol-acid reductoisomerase, a central catalyst of a cell-free enzyme cascade for the manufacture of platform chemicals, Applied BioSciences,

Zev S, Ringel M, Driller R, Loll B, Brück T, Major DT. (2022) Understanding the competing pathways leading to hydropyrene and isoelisabethatriene, Beilstein Journal of Organic Chemistry,

Paper M, Glemser M, Haack M, Lorenzen J, Mehlmer N, Fuchs T, Schenk G, Garbe D, Weuster-Botz D, Eisenreich W, Lakatos M, Brück T. (2022) Efficient Green Light Acclimation of the Green Algae Picochlorum sp. Triggering Geranylgeranylated Chlorophylls, Frontiers in Bioengineering and Biotechnology, doi: 10.3389/fbioe.2022.885977

Ringel M, Dimos N, Himpich S, Haack M, Huber C, Eisenreich W, Schenk G, Loll B, Brück T. (2022) Biotechnological potential and initial characterization of two novel sesquiterpene synthases from Basidiomycota Coniophora puteana for heterologous production of δ‑cadinol, Microbial Cell Factories, 21:64, doi: 10.1186/s12934-022-01791-8

Prem S, Helmer C O, Dimos N, Himpich S, Brück T, Garbe D, Loll B. (2022) Towards an understanding of oleate hydratases and their application in industrial processes, Microbial Cell Factories, 21:58, doi: 10.1186/s12934-022-01777-6

Pakbin B, Zolghadr L, Rafiei S, Brück W M, Brück T B. (2022) FTIR differentiation based on genomic DNA for species identification of Shigella isolates from stool samples, Scientific Reports, 17;12(1):2780, doi: 10.1038/s41598-022-06746-y

Jurkowski W, Paper M, Brück T. (2022) Isolation and Investigation of Natural Rare Earth Metal Chelating Agents From Calothrix brevissima - A Step Towards Unraveling the Mechanisms of Metal Biosorption, Frontiers in Bioengineering and Biotechnology, doi: 10.3389/fbioe.2022.833122



Wieland K, Masri M, von Poschinger J, Brück T, Haisch C. (2021) Non-invasive Raman spectroscopy for time-resolved in-line lipidomics, RSC Advances, 11, 28565-28572,

Younes S, Awad D, Kassab E, Haack M, Schuler C, Mehlmer N, Brück T. (2021) Systems Biology Engineering of the Pantothenate Pathway th Enhance 3HB Productivity in Escherichia coli, Biotechnology and Bioprocess Engineering, 26, 621-629 (2021),

Shaigani P, Awad D, Redai V, Fuchs M, Haack M, Mehlmer N, Brück T. (2021) Oleaginous yeasts - substrate preference and lipid productivity: a view on the performance of microbial lipid producers, Microbial Cell Factories, (2021) 20:220,

Fuchs T, Melcher F, Rerop Z S, Lorenzen J, Shaigani P, Awad D, Haack M, Prem S A, Masri M, Mehlmer N, Brück T B. (2021) Identifiying carbohydrate-active enzymes of Cutaneotrichosporon oleaginosus using systems biology, Microbial Cell Factories, (2021) 20:205;

Fuchs T, Arnold N D, Garbe D, Deimel S, Lorenzen J, Masri M, Mehlmer N, Weuster-Botz D, Brück T. (2021) A Newly Designed Automatically Controlled, Sterilizable Flat Panel Photobioreactor for Axenic Algae Culture, Frontiers in Bioengineering and Biotechnology, Volume 9, Article 697354,

Portner B W, Endres C H, Brück T, Garbe D. (2021) Life cycle greenhouse gas emissions of microbial fuel from thin-layer cascades, Bioprocess and Biosystems Engineering, 44, 2399-2406 (2021),

Wilson L A, Knaven E G, Morris M T, Monteiro Pedroso M, Schofield C J, Brück T B, Boden M, Waite D W, Hugenholtz P, Guddat L, Schenk G. (2021) Kinetic and Structural Characterization of the First B3 Metallo-ß-Lactamase with an Active-Site Glutamic Acid, Antimicrobial Agents and Chemotherapy, Volume 65, Number 10,

Schädler T, Thurn AL, Brück T, Weuster-Botz D. (2021) Continuous Production of Lipids with Microchloropsis salina in Open Thin-Layer Cascade Photobioreactors on a Pilot Scale, Energies, Volume 14, Issue 500;


Ringel M, Reinbold M, Hirte M, Haack M, Huber C, Eisenreich W, Masri MA, Schenk G, Guddat LW, Loll B, Kerr R, Garbe D, Brück TB. (2020) Towards a sustainable generation of pseudopterosin-type bioactives, Green Chemistry, Volume 22, pp 6033-6046

Raz K, Driller R, Dimos N, Ringel M, Brück T, Loll B, Major DT. (2020) The Impression of a Nonexisting Catalytic Effect: The Role of CotB2 in Guiding the Complex Biosynthesis of Cyclooctat-9-en-7-ol, Journal of the American Chemical Society, Volume 142, Issue 51, pp 21562-21574

Raz K, Driller R, Brück T, Loll B, Major DT. (2020) Understanding the role of active site residues in CotB2 catalysis using a cluster model, Beilstein Journal of Organic Chemistry, Volume 16, pp 50-59

Awad D, Younes S, Glemser M, Wagner FM, Schenk G, Mehlmer N, Brück T. (2020) Towards high-throughput optimization of microbial lipid production: from strain development to process monitoring, Sustainable Energy and Fuels, Volume 4, 5958-5969

Arnold U, Brück T, Battenberg A, Masri M. (2020) PtX‐Plus: Synergies Through Coupling of PtX Facilities with a Biorefinery, Chemie Ingenieur Technik, Volume 92, Issue 11, pp 1797-1902

Woortman DV, Jürgens S, Untergehrer M, Rechenberger J, Fuchs M, Mehlmer N, Qoura F, Eckel G, Stöhr M, Oßwald P, Le Clercq P, Hintermann L, Weuster-Botz D, Bracher F, Brück T. (2020) Greener aromatic antioxidants for aviation and beyond, Sustainable Energy and Fuels, Volume 4, pp 2153-2163

Woortman DV, Haack M, Mehlmer N, Brück TB. (2020) Additive Analytics: Easy Transformation of Low-Cost Fused Deposition Modeling Three-Dimensional Printers for HPTLC Sample Application, ACS Omega, Volume 5, Issue 19, pp 11147-11150

Arnold ND, Brück WM, Garbe D, Brück TB. (2020) Enzymatic Modification of Native Chitin and Conversion to Specialty Chemical Products, Marine Drugs, Volume 18, Issue 93

Younes S, Bracharz F, Awad D, Qoura F, Mehlmer N, Brück T. (2020) Microbial lipid production by oleaginous yeasts grown on Scenedesmus obtusiusculus microalgae biomass hydrolysate, Bioprocess and Biosystems Engineering, Volume 43, pp 1629-1638

Wun SJ, Johnson LA, You L, McGeary RP, Brück T, Schenk G, Guddat LW. (2020) Inhibition studies of ketol-acid reductoisomerases from pathogenic microorganisms, Archives of Biochemistry and Biophysics, Volume 692

Selleck C, Pedroso MM, Wilson L, Krco S, Knaven EG, Miraula M, Mitic M, Larrabee JA, Brück T, Clark A, Guddat LW, Schenk G. (2020) Structure and mechanism of potent bifunctional β-lactam- and homoserine lactone-degrading enzymes from marine microorganisms, Scientific Reports, Volume 10, pp 12882

Schädler T, Neumann-Cip A-C, Wieland K, Glöckler D, Haisch C, Brück T, Weuster-Botz D (2020): High-density microalgae cultivation in open thin-layer cascade photobioreactors with water recycling, Appl Sci 10: 3883.

Jurkowski W, Heilmann M, Becker AM, Buchholz R, Brück TB. (2020) Terbium Excitation Spectroscopy as a Detection Method for Chromatographic Separation of Lanthanide-Binding Biomolecules, ACS Omega, Volume 5, pp 27050-27056

Woortman DV, Fuchs T, Striegel L, Fuchs M, Weber N, Brück TB, Rychlik M. (2020) Microalgae a Superior Source of Folates: Quantification of Folates in Halophile Microalgae by Stable Isotope Dilution Assay, Frontiers in Bioengineering and Biotechnology, Volume 7, Article 481

Schrepfer P, Ugur I, Klumpe S, Loll B, Kaila VRI, Brück T. (2020) Exploring the catalytic cascade of cembranoid biosynthesis by combination of genetic engineering and molecular simulations, Computational and Structural Biotechnology, Volume 18, pp 1819-1829


Driller, R.; Garbe, D.; Mehlmer, N.; Fuchs, M.; Raz, K.; Major, D. T.; Brück, T. B.; Loll B., Current understanding and biotechnological application of the bacterial diterpene synthase CotB2. Beilstein Journal of Organic Chemistry 2019.

Striegel, L.; Fuchs, T.; Woortman, D. V.; Fuchs, M.; Weber, N.; Brueck, T. B.; Rychlik, M., Microalgae a superior source of folates: Quantification of folates in halophile microalgae by stable isotope dilution assay. Frontiers in Bioengineering and Biotechnology 2019.

Schädler, T.; Cerbon, D. C.; de Oliveira, L.; Garbe, D.; Brück, T.; Weuster-Botz, D., Production of lipids with microchloropsis salina in open thin-layer cascade photobioreactors. Bioresource Technology 2019, 121682.

Masri, M. A.; Garbe, D.; Mehlmer, N.; Brück, T. B., A sustainable, high-performance process for the economic production of waste-free microbial oils that can replace plant-based equivalents. Energy & Environmental Science 2019, 12, 2717 – 2732

Kassab, E.; Mehlmer, N.; Brueck, T., Systematic engineering of the Escherichia coli fatty acid biosynthesis for the production of very long chain fatty acids. Frontiers in Bioengineering and Biotechnology 2019.

Kassab, E.; Haack, M.; Fuchs, M.; Mehlmer, N.; Brueck, T., Engineering Escherichia coli FAB system using synthetic plant genes for the production of long chain fatty acids. Microbial Cell Factories 2019.

Braun, M. K.; Lorenzen, J.; Masri, M.; Liu, Y.; Baráth, E.; Brück, T.; Lercher, J. A., Catalytic decomposition of the oleaginous yeast Cutaneotrichosporon oleaginosus and subsequent biocatalytic conversion of liberated free fatty acids. ACS Sustainable Chemistry & Engineering 2019, 7 (7), 6531-6540.

Bessadok, B.; Santulli, A.; Brück, T.; Sadok, S., Species disparity response to mutagenesis of marine yeasts for the potential production of biodiesel. Biotechnology for Biofuels 2019, 12 (1), 129.

Awad, D.; Bohnen, F.; Mehlmer, N.; Brueck, T., Multi-factorial-guided media optimization for enhanced biomass and lipid formation by the oleaginous yeast Cutaneotrichosporon oleaginosus. Frontiers in Bioengineering and Biotechnology 2019, 7, 54.

Adamietz, T.; Jurkowski, W.; Adolph, J.; Brück, T. B., Biogas yields and composition from oil-extracted halophilic algae residues in conventional biogas plants operated at high salinities. Bioprocess and Biosystems Engineering 2019, 1-8.

Awad D, Brück T. (2019) Optimization of protein isolation by proteomic qualification from Cutaneotrichosporon oleaginosus, Analytical and Bioanalytical Chemistry, Volume 412, pp 449-462


Arnold, U., Brück, T., De Palmenaer, A., & Kuse, K. (2018). Carbon Capture and Sustainable Utilization by Algal Polyacrylonitrile Fiber Production: Process Design, Techno-Economic Analysis, and Climate Related Aspects. Industrial & Engineering Chemistry Research, 57(23), 7922-7933. doi:10.1021/acs.iecr.7b04828

Arnold, U., De Palmenaer, A., Brück, T., & Kuse, K. (2018). Energy-Efficient Carbon Fiber Production with Concentrated Solar Power: Process Design and Techno-economic Analysis. Industrial & Engineering Chemistry Research, 57(23), 7934-7945. doi:10.1021/acs.iecr.7b04841

Driller, R., Janke, S., Fuchs, M., Warner, E., Mhashal, A. R., Major, D. T., Christmann, M., Brück, T., & Loll, B. (2018). Towards a comprehensive understanding of the structural dynamics of a bacterial diterpene synthase during catalysis. Nature Communications, 9(1), 3971. doi:10.1038/s41467-018-06325-8

Endres, C. H., Roth, A., & Brück, T. B. (2018). Modeling Microalgae Productivity in Industrial-Scale Vertical Flat Panel Photobioreactors. Environmental Science & Technology, 52(9), 5490-5498. doi:10.1021/acs.est.7b05545

Escorcia, A. M., van Rijn, J. P. M., Cheng, G. J., Schrepfer, P., Bruck, T. B., & Thiel, W. (2018). Molecular dynamics study of taxadiene synthase catalysis. J Comput Chem. doi:10.1002/jcc.25184

Gnouma, A., Sehli, E., Medhioub, W., Ben Dhieb, R., Masri, M., Mehlmer, N., Slimani, W., Sebai, K., Zouari, A., Brück, T., & Medhioub, A. (2018). Strain selection of microalgae isolated from Tunisian coast: characterization of the lipid profile for potential biodiesel production. Bioprocess and Biosystems Engineering. doi:10.1007/s00449-018-1973-5

Hirte, M., Meese, N., Mertz, M., Fuchs, M., & Brück, T. B. (2018). Insights Into the Bifunctional Aphidicolan-16-ß-ol Synthase Through Rapid Biomolecular Modeling Approaches. Frontiers in Chemistry, 6(101). doi:10.3389/fchem.2018.00101

Hirte, M., Mischko, W., Kemper, K., Röhrer, S., Huber, C., Fuchs, M., Eisenreich, W., Minceva, M., & Brück, T. B. (2018). From microbial upcycling to biology-oriented synthesis: combining whole-cell production and chemo-enzymatic functionalization for sustainable taxanoid delivery. Green Chemistry. doi:10.1039/C8GC03126F

M., E. A., M., v. R. J. P., Gui-Juan, C., Patrick, S., B., B. T., & Walter, T. (2018). Molecular dynamics study of taxadiene synthase catalysis. Journal of Computational Chemistry, 39(19), 1215-1225. doi:doi:10.1002/jcc.25184

Mahmoud, M., Samer, Y., Martina, H., Farah, Q., Norbert, M., & Thomas, B. (2018). A Seagrass-Based Biorefinery for Generation of Single-Cell Oils for Biofuel and Oleochemical Production. Energy Technology, 6(6), 1026-1038. doi:doi:10.1002/ente.201700604

Masri, M. A., Jurkowski, W., Shaigani, P., Haack, M., Mehlmer, N., & Brück, T. (2018). A waste-free, microbial oil centered cyclic bio-refinery approach based on flexible macroalgae biomass. Applied Energy, 224, 1-12. doi:

Mischko, W., Hirte, M., Fuchs, M., Mehlmer, N., & Bruck, T. B. (2018). Identification of sesquiterpene synthases from the Basidiomycota Coniophora puteana for the efficient and highly selective beta-copaene and cubebol production in E. coli. Microb Cell Fact, 17(1), 164. doi:10.1186/s12934-018-1010-z

Mischko, W., Hirte, M., Roehrer, S., Engelhardt, H., Mehlmer, N., Minceva, M., & Brück, T. (2018). Modular biomanufacturing for a sustainable production of terpenoid-based insect deterrents. Green Chemistry, 20(11), 2637-2650. doi:10.1039/c8gc00434j

Schinkovitz, A., Boisard, S., Freuze, I., Osuga, J., Mehlmer, N., Brück, T., & Richomme, P. (2018). Matrix-free laser desorption ionization mass spectrometry as a functional tool for the analysis and differentiation of complex phenolic mixtures in propolis: a new approach to quality control. Analytical and Bioanalytical Chemistry. doi:10.1007/s00216-018-1225-1

Severin, T. S., Apel, A. C., Brück, T., & Weuster-Botz, D. (2018). Investigation of vertical mixing in thin-layer cascade reactors using computational fluid dynamics. Chemical Engineering Research and Design, 132, 436-444. doi:10.1016/j.cherd.2018.01.036

Sieber, V., Hofer, M., Brück, W. M., Garbe, D., Brück, T., & Lynch, C. A. (2018). ChiBio: An Integrated Bio-refinery for Processing Chitin-Rich Bio-waste to Specialty Chemicals. In P. H. Rampelotto & A. Trincone (Eds.), Grand Challenges in Marine Biotechnology (pp. 555-578). Cham: Springer International Publishing.


Apel, A. C., Pfaffinger, C. E., Basedahl, N., Mittwollen, N., Göbel, J., Sauter, J., Brück, T., & Weuster-Botz, D. (2017). Open thin-layer cascade reactors for saline microalgae production evaluated in a physically simulated Mediterranean summer climate. Algal Research, 25, 381-390. doi:

Bracharz, F., Beukhout, T., Mehlmer, N., & Brück, T. (2017). Opportunities and challenges in the development of Cutaneotrichosporon oleaginosus ATCC 20509 as a new cell factory for custom tailored microbial oils. Microbial Cell Factories, 16(1), 178. doi:10.1186/s12934-017-0791-9

Bracharz, F., Redai, V., Bach, K., Qoura, F., & Bruck, T. (2017). The effects of TORC signal interference on lipogenesis in the oleaginous yeast Trichosporon oleaginosus. BMC Biotechnol, 17(1), 27. doi:10.1186/s12896-017-0348-3

Janke, R., Fuchs, M., Christmann, M., Brück, T., & Loll, B. (2017). Herstellung von polyzyklischen Diterpenen. BIOspektrum, 23(6), 709-711. doi:10.1007/s12268-017-0858-5

Kemper, K., Hirte, M., Reinbold, M., Fuchs, M., & Bruck, T. (2017). Opportunities and challenges for the sustainable production of structurally complex diterpenoids in recombinant microbial systems. Beilstein J Org Chem, 13, 845-854. doi:10.3762/bjoc.13.85

Kracht, O. N., Ammann, A.-C., Stockmann, J., Wibberg, D., Kalinowski, J., Piotrowski, M., Kerr, R., Brück, T., & Kourist, R. (2017). Transcriptome profiling of the Australian arid-land plant Eremophila serrulata (A.DC.) Druce (Scrophulariaceae) for the identification of monoterpene synthases. Phytochemistry, 136, 15-22. doi:

Lorenzen, J., Driller, R., Waldow, A., Qoura, F., Loll, B., & Brück, T. (2017). Rhodococcus erythropolis Oleate Hydratase: a New Member in the Oleate Hydratase Family Tree—Biochemical and Structural Studies, 10(2), 407-414. doi:10.1002/cctc.201701350

Lorenzen, J., Igl, N., Tippelt, M., Stege, A., Qoura, F., Sohling, U., & Brück, T. (2017). Extraction of microalgae derived lipids with supercritical carbon dioxide in an industrial relevant pilot plant. Bioprocess and Biosystems Engineering, 40(6), 911-918. doi:10.1007/s00449-017-1755-5

Qaroush, A. K., Assaf, K. I., Bardaweel, S. K., Al-Khateeb, A. a., Alsoubani, F., Al-Ramahi, E., Masri, M., Brück, T., Troll, C., Rieger, B., & Eftaiha, A. a. F. (2017). Chemisorption of CO2 by chitosan oligosaccharide/DMSO: organic carbamato–carbonato bond formation. Green Chemistry, 19(18), 4305-4314. doi:10.1039/C7GC01830D

Severin, T. S., Plamauer, S., Apel, A. C., Brück, T., & Weuster-Botz, D. (2017). Rapid salinity measurements for fluid flow characterisation using minimal invasive sensors. Chemical Engineering Science, 166, 161-167. doi:

Vagin S I, Kronast A, Altenbuchner P T, Adams F, Sinkel C, Deglmann P, Loos R, Schuffenhauer T, Sommer B, Brück T, Rieger B. (2017) Enzymatic degradation of synthetic poly(3-hydroxybutyrates) as tool for combinatorial microstructure determination, Polymer Degradation and Stability, Volume 143, pp 176 - 185,


Reiße, S., Haack, M., Garbe, D., Sommer, B., Steffler, F., Carsten, J., Bohnen, F., Sieber, V., Brück, T. (2016) In Vitro Bioconversion of Pyruvate to n-Butanol with Minimized Cofactor Utilization Front. Bioeng. Biotechnol., DOI: 10.3389/fbioe.2016.00074

Görner, C., Schrepfer, P., Redai, V., Haslbeck, M., Wallrapp, F., Loll, B., Eisenreich, W., Brück, T. (2016) Identification, characterization and molecular adaptation of class I redox systems for the production of hydroxylated diterpenoids. Microb.Cell.Fac. 15:86, DOI: 10.1186/s12934-016-0487-6

Endres, C., Roth, A., Brück, T. (2016) A thermal reactor model for large-scale algae cultivation in vertical flat panel photobioreactor. Enivr. Sci. Eng. 50(7):3920-7, DOI: 10.1021/acs.est.5b05414


Schrepfer, P., Görner, C., Redai, V., Büttner, A., Hertel, M., Wallrapp, F., Eisenreich, W., Sieber, V., Kourist, R., Brück, T. (2015) Identification of amino acid networks governing catalysis in the closed complex of class I terpene synthases. P.N.A.S. doi: 10.1073/pnas.1519680113

Glemser, M., Heining, M., Schmidt, J., Becker, A., Buchholz, R., Brück, T. (2015) Application of light-emitting diodes (LEDs) in cultivation of phototrophic microalgae: current state and perspectives. Appl.Microb.Biotech. 12, 1-12 (doi: 10.1007/s00253-015-7144-6).

Görner, C., Redai, V., Bracharz, F., Schrepfer, P., Garbe, D., Brück, T. (2015) Genetic engineering and production of modified fatty acids by the non-conventional oleaginous yeast Trichosporon oleaginosus ATCC 20509. Green Chem. (doi: 10.1039/c5gc01767j)

Kourist, R., Bracharz, F., Lorenzen, J., Kracht, O.N., Chovatia, M., Daum, C., Deshpande, S., Lipzen, A., Nolan, M., Ohm, R.A., Grigoriev, I.V., Sun, S., Heitman, J., Brück, T and Nowrousian, M. (2015) Genomics and Transcriptomics Analyses of the Oil-Accumulating Basidiomycete Yeast Trichosporon oleaginosus: Insights into Substrate Utilization and Alternative Evolutionary Trajectories of Fungal Mating Systems. mBio 6(4), e00918-15. (doi: 10.1128/mBio.00918-15)

Görner, C., Hirte, M., Huber, S., Schrepfer, P., Brück, T. (2015) Stereoselective chemo-enzymatic oxidation routes for (1R,3E,7E,11S,12S)-3,7,18-dolabellatriene. Front. Microbiol. 6, 1115. (doi: 10.3389/fmicb.2015.01115)

Heilmann, M., Jurkowski, W., Buchholz, R., Brueck, T., Becker, A.M., (2015) Biosorption of Neodymium by Selected Photoautotrophic and Heterotrophic Species. J. Chem. Eng. Process Technol. 6, 4 (

Brück, W.M., Bracharz, F., Brück, D.W., Brück, T.B., (2015) Mikrobiologische Nutzung von Fischerei-Abfall: Von der Krebsschale in die Creme. Biologie unserer Zeit. 3 (45), 160-167 (doi:10.1002/ biuz.201510561)

Qoura, F., Kassab, E., Reiße, S., Antranikian, G, Brück, T. (2015) Characterization of a thermo-active subtilisin-like serine protease from the psychrophilic bacterium Shewanella arctica. J. Mol.Cat. B, Enzymatic. 116, 16–23

Reiße, S., Garbe, D., Brück, T. (2015) Identification and optimization of a novel thermo- and solvent stable ketol-acid reductoisomerase for cell free isobutanol biosynthesis. Biochimie 108, 76-84

Sommer, B., von Moeller, H., Haack, M., Qoura, F., Langner, C., Bourenkov, G., Garbe, D., Loll, B., Brück, T. (2015) Detailed structure-function correlations of Bacillus subtilis Acetolactate Synthase. ChemBioChem 16 (1), 110-18

Brück, W., Bracharz, F., Brück, D. W. and Brück, T. B. (2015), Von der Krebsschale in die Creme. Biologie in unserer Zeit, 45: 160–167. doi: 10.1002/biuz.201510561

Reiße, S., Garbe, D., Brück, T. (2015) Identification and optimization of a novel thermo- and solvent stable ketol-acid reductoisomerase for cell free isobutanol biosynthesis. Biochimie 108, 76-84

Brück WM, Bracharz F, Brück DW, Brück TB. Mikrobiologische Nutzung von Fischerei-Abfall: Von der Krebsschale in die Creme, (2015), Biologie unserer Zeit, Volume 45 Issue 3 pp 160-167


Brück, T.B., Kourist, R., Loll, B. (2014) Production of macrocyclic sesqui- and diterpenes in heterologous microbial hosts: A systems approach to harness nature's molecular diversity ChemCatChem 6 (5), 1142–1165

Janke, R., Görner, C., Hirte, M., Brück, T.B., Loll, B. (2014) Crystal structure of the first bacterial diterpene cyclase: CotB2. Acta Cryst. D 70, 1528-1537

Reiße, S., Garbe, D., Brück, T. (2014) Meiothermus ruber thiolase - a new process stable enzyme for improved butanol synthesis. Biochimie 103, 16-22

Qoura, F., Brück, T., Antranikian, G. (2014) The psychrophile Shewanella arctica sp. nov.: a new source of industrially important enzyme systems. JSM Biotechnology and Biomedical Engineering 2 (1), 1026-35

Garbe, D., Reiße, S., Brück, T. (2014) Biomasse-basierte Lipide: Nachhaltige Bausteine für die Kunststoff-Herstellung. Chemie in unserer Zeit 48 (4), 284-95

Qoura, F., Elleuche, S., Brück, T., Antranikian, G. (2014) Purification and characterization of a cold-adapted pullulanase from a psychrophilic bacterial isolate. Extremophiles 18, 1095-102

Qoura, F., Kassab, E., Reiße, S., Antranikian, G, Brueck, T. (2014) Characterization of a thermo-active subtilisin-like serine protease from the psychrophilic bacterium Shewanella arctica. Journal of Molecular Catalysis. B, Enzymatic.


Bohnen F, Brück TB. A critical review of algae process optimization using design of experiment methodologies (2013) JSM Biotechnol.Bioeng. 1(3), 1015

Sommer B, Garbe D, Brück TB. Catalytic modules in non-natural butanol biosynthesis: Conversion of the key intermediate crotylalcohol to n-butanol via a designed enzyme cascade, (2013) JSM Biotechnol.Bioeng. 1(2), 1010

Sommer B, Garbe D, Schrepfer P, Brück T. Characterization of a highly thermostable ß-hydroxybutyryl CoA dehydrogenase from Clostridium acetobutylicum ATCC 824, (2013) Journal of Molecular Catalysis. B, Enzymatic Volume 98, pp. 138–144

Brück TB, Bohnen F. The Biodiesel Dilemma: A techno- and socioeconomic review of EU legislative actions, (2013) JSM Biotechnol.Bioeng. 1(2), 1009

Görner C, Häuslein I, Schrepfer P, Eisenreich W, Brück TB. Targeted engineering of cyclooctat-9-en-7-ol synthase: A stereospecific access to two new, non-natural fusicoccane-type diterpenes, (2013) Chem.Cat.Chem.  5, pp. 3289–3298

Zhao C, Brück TB, Lercher JA. Catalytic deoxygenation of microalgae oil to green hydrocarbons, (2013) Green Chem 15, 1720-1739

Brück WM, Gibson GR, Brück TB. The effect of proteolysis on the induction of cell death by monomeric alpha-lactalbumin, (2013) Biochimie Volume 97, pp 138-143


Guterl JK, Garbe D, Carsten J, Steffler F, Sommer B, Reiße S, Philipp A, Haack M, Rühmann B, Koltermann A, Kettling U, Brück T, Sieber V. Cell-free metabolic engineering: production of chemicals by minimized reaction cascades. (2012) Chem Sus Chem 5, pp. 2165-72

Brück TB, Brück DW. Oxidative metabolism of the anti-cancer agent mitoxantrone by horseradish, lacto-and lignin peroxidase.(2011) Biochimie 93, pp. 217-26

Brück WM, Brück TB, Self WT, Reed JK, Nitecki SS, McCarthy PJ. Comparison of the anaerobic microbiota of deep water Geodia sp. and sandy sediments in the Florida straits, (2010) ISME J 4, pp. 686-699 

Ranzer L, Brueck TB, Lopez J, Kerr RG. A new prokaryotic farnesyldiphosphate synthase from the octocoral Eunicea fusca: differential display, inverse PCR, cloning, and characterization, (2009) Mar Biotechnol (NY) 11(1), pp. 62-73

Al-Ghoul M, Brück TB, Lauer-Fields JL, Asirvatham VS, Zapata C, Kerr RG, Fields GB. Comparative proteomic analysis of matched primary and metastatic melanoma cell lines, (2008) J  Proteome Res  7(9), pp. 4107-18

Santiago LZ, Brück TB, Brück WB, Kerr RG. The diversity of the bacterial communities associated with the azooxanthellate hexacoral Cirrhipathes leutkeni, (2007) ISME J  1, pp. 654-659

Brück TB, Brück WM, Santiago-Vasquez LZ, McCarthy P, Kerr RG. Diversity of the bacterial communities associated with the azooxanthellate deep water octocorallia Leptogorgia minimata, Iciligorgia schrammi and Swiftia exertia, (2007) Mar Biotech 9, pp. 1-1

Brück TB, Kerr RG. Purification and kinetic properties of elisabethatriene synthase from the coral Pseudopterogorgia elisabethae, (2006). Comp Biochem Physiol B 143, pp. 295-302

Brück TB, Harvey PJ. Proteomics: advances, challenges and frontiers, (2005) The Biomedical Scientist 6, pp. 554-564

Brück TB, Harvey PJ. Oxidation of mitoxantrone by lactoperoxidase (2003) Biochim Biophys Acta 1649, pp. 154-163

Brück TB, Gerini MF, Baciocchi E, Harvey PJ. Oxidation of thioanisole and p-methoxythioanisole by lignin peroxidase: kinetic evidence of a direct reaction between Compound II and a radical cation, (2003) Biochem J 374, pp. 761-766

Brück TB, Harvey PJ. Spectrophotometric investigations with hexa-coordinate ferric lignin peroxidase, (2002) Biochem Biophys. Res. Comm. 297, pp. 406-411

Brück TB, Fielding RJ, Symons MCR, Harvey PJ. Mechanism of nitrite stimulated catalysis by lactoperoxidase, (2001) Eur J Biochem. 268, pp. 3214-3222

Brueck TB, Simpson D, Hoban P, Clayton RN, Farrell WC. Amplification of the Cyclin D1 gene in primary pituitary tumours, (1997) J Endocrinol  155, pp. 20-21


  • Cavelius, P, Engelhart-Straub, S, Heieck, K, Pilz, M, Melcher, F and Brück, T. " Agricultural Biocatalysis: From Waste Stream to Food and Feed Additives". (2022) in Agricultural Biocatalysis - Theoretical Studies and Photosynthesis Aspects ed. P. Jeschke and E. B. Starikov, pp 133-182, Jenny Stanford Publishing,
  • Melcher, Felix, Paper, Michael and Brück, Thomas B.. "9 Photosynthetic conversion of CO2 into bioenergy and materials using microalgae". (2021) in Photosynthesis: Biotechnological Applications with Microalgae ed. M. Rögner, pp 227-254, Walter C. De Gruyter,
  • Harkin C, Mehlmer N, Woortman DV, Brück TB, Brück WM. Nutritional and Additive Uses of Chitin and Chitosan in the Food Industry, (2019) in Sustainable Agriculture Reviews 36, pp 1-43, Springer
  • Brück WM, Reiße S, Garbe G, Brück TB. Industry potential of marine bioactive compounds: Downstream Processing and Vehicles for efficient delivery, (2011) in Marine Bioactive Compounds Sources, Characterisation and applications ed. Hayes M. Springer
  • Brück TB, Garbe G. Algae symbiosis with eukayotic partners, (2012) in Microalgal Biotechnology: Potential and Production ed. Posten C., Walter C. De Gryter
  • Brück WM, Reisse S, Garbe D, Brück TB. Industry Potential of Marine Bioactive Components: Downstream Processing and Vehicles for Efficient Delivery In Situ, (2011), in Marine Bioactive Compounds, pp 129-157, Springer


  • EP 3933038 Modified terpene synthases and their use for production of pseudopterosin intermediates and/or pseudopterosins. M Ringel, T Brück, M Reinbold, D Garbe
  • WO2019063718 A process for the cell-free enzymatic production of 10-hydroxystearic acid (10-HSA) from bio-based oils for lubricant formulation. J Lorenzen, T Brück
  • WP 309297 Sustainable supply of bioactive marine products. RG Kerr, TB Brück 
  • WO/2008/113585 Generation of chemical building blocks from plant biomass by selective hydrolysis. A Koltermann, M Rarbach, TB Brück, U Kettling 
  • EP09161030.3. Liquified biomass. A Koltermann, TB Brück, M Rarbach, U Kettling, Z Dragovic, A Kohl, I Bessler, J Gerlach 
  • EP09180210 Thermostable xylanases for the selective hydrolysis of pentose-containing polysaccharides. TB Brück, I Beßler, M Rarbach, C Reisinger, A Koltermann, A Kohl, U Kettling, G Hreggvidsson, D Fridjonsson 
  • EP10153355.2 Optimized Cellulase Enzymes. TB Brück, C Reisinger, M Rarbach, J Gerlach, I Beßler, J-C Pieck, A Koltermann, L Röcher, D Schlosser, A Kohl, U Kettling, J Claren 
  • WO2012139743 Environment friendly method for the production of cement. TB Brück, FM Bohnen, R Sood 
  • EP12181085.7 Cell-free and minimized metabolic reaction cascades for the production of chemicals. T Brück, D Garbe, J-K Guterl, V Sieber, M Kraus, M Zavrel, U Kettling
  • WO/2012/089844 Efficient lignocellulose hydrolysis with integrated enzyme production Brück, Thomas; Rarbach, Markus;  Dragovic, Zdravko;  Kohl, Andreas; Gerlach, Jochen; Bartuch, Jörg
  •  EP3536800A1 Extraction of renewable triglycerides from oleaginous microorganisms. U Sohling, A Stege, G Schirrmacher, M Masri, T Brück
  • EP3696273 A method for producing microbial lipids, M Masri, T Brück