Technische Universität München
Professur für Organische Chemie (Prof. Hintermann)
Lichtenbergstr. 4
85748 Garching b. München
Catalytic Methods for Organic Synthesis
Our research focus lies in the development of highly active and selective catalysts based on metal complexes or small organic molecules for sustainable organic synthesis (SOS). Such catalysts can be used both in basic molecular basic research and industrial production. Particularly, we want to develop waste-free (atom-economic) processes for achieving synthetic efficiency. In this manner, resources can be saved and application risks towards humans and the environment will be reduced (see research overview).
Chemistry - A European Journal
Abstract: Syntheses of (partially) aromatic nitrogen heterocycles increasingly rely on transition-metal catalyzed C−C- and C−N-cross-coupling reactions. Here we describe a different approach to the synthesis of…
Journal of Organic Chemistry
Abstract: The addition of diarylmethanes or methylarenes via activation of benzylic C(sp3)-H bonds to N-aryl imines proceeds under catalysis by alkali hexamethyldisilazide (HMDS) base to give…
Organometallics
Abstract: Attaching di(1R)-menthylphosphino fragments (menthyl = Men = 1R,2S,5R-2-isopropyl-5-methylcyclohex-1-yl) to molecular scaffolds turns them into homochiral, bulky, electron-rich phosphine ligands with…
Helvetica Chimica Acta
Abstract: A group of transition-metal catalyzed hydrogen moving reactions, encompassing hydrogen autotransfer (HAT; also called borrowing hydrogen, BH), dehydrogenative condensation (DHC) and alkene…
ChemCatChem
Abstract: A HOT-CAT (homogeneous thermal catalysis) screen using microwave-heating and quantitative NMR (qNMR) analysis has been developed for identification and comparison of catalyst activity in homogeneous…
Chimia
Abstract: Some 70 years ago, the reaction of diacetyl (1) and arylamines (2) in hot phosphoric acid was reported to give a new type of condensation products, but no structure was assigned to them. The case is…
Chemistry - A European Journal
Abstract: The generation of arylzinc reagents (ArZnX) by direct insertion of zinc into the C−X bond of ArX electrophiles has typically been restricted to iodides and bromides. The insertions of zinc dust into…
Sustainable Energy and Fuels
Abstract: Antioxidants (AO) inhibiting unspecific oxygen reactions are added to most susceptible industrial products, including liquid hydrocarbon-based aviation fuels. Regulatory approved jet fuel, whether…
European Journal of Organic Chemistry
Abstract: Axially chiral, enantiopure 1,1'-binaphthyl-2-carboxylic acids (BINA-Cox) have recently been introduced as chiral ligands for transition metal catalysis. Together with equimolar, co-catalytic amounts…
Journal of Organic Chemistry
Abstract: Menthyl Grignard reagent 1 from either menthyl chloride (2) or neomenthyl chloride (3) consists of menthylmagnesium chloride (1a), neomenthylmagnesium chloride (1b),…
