Quantitative bioanalytical chemistry is a dynamic and interdisciplinary research field dedicated to the development of advanced analytical platforms—such as biosensors, ELISAs, microarrays, and lateral flow assays—for the rapid and precise quantification of bioorganic analytes. These include pharmaceuticals, toxins, and pathogens, detected through antibody-based recognition or molecular biological techniques.

Our vision is to push the boundaries of bioanalytical innovation by identifying and implementing novel applications in water quality monitoring, food safety analysis, and clinical diagnostics. By integrating cutting-edge detection technologies with robust quantification strategies, we aim to contribute to global health, environmental sustainability, and consumer protection through faster, more accessible, and highly sensitive analytical solutions.

Key publication:

Kloth, K.; Rye-Johnsen, M.; Didier, A.; Dietrich, R.; Märtlbauer E.; Niessner, R.; Seidel, M., A regenerable immunochip for the rapid determination of 13 different antibiotics in raw milk. The Analyst, 2009, 134, 1433 - 1439.

Klüpfel, J.; Koros, R.C.; Dehne, K.; Ungerer, M.; Würstle, S.; Mautner, J.; Feuerherd, M.; Protzer, U.; Hayden, O.; Elsner, M.; Seidel, M. Automated, flow-based chemiluminescence microarray immunoassay for the rapid multiplex detection of IgG antibodies to SARS-CoV-2 in human serum and plasma (CoVRapid CL-MIA). Analytical and Bioanalytical Chemsitry, 2021, 413, 5619-5632, 
https://link.springer.com/article/10.1007/s00216-021-03315-6.

Szkola, A.; Campbell, K.; Elliott, C.P.; Niessner, R.; Seidel, M., Automated, high performance, flow-through chemiluminescence microarray for the multiplexed detection of phycotoxins. Analytica Chimica Acta, 2013, 797, 211-218, dx.doi.org/10.1016/j.aca.2013.05.028.

Sollweck, K.; Streich, P.; Elsner M.; Seidel, M. A chip-based colony fusion recombinase polymerase amplification assay for monitoring of antimicrobial resistance genes and their carrying species in surface water. ACS ES&T Water, 2021, 
doi.org/10.1021/acsestwater.0c00110.