64. J.Neumair, M. Elsner and M. Seidel. Flow-Based Chemiluminescence Microarrays as Screening Platform for Affinity Binders to Capture and Elute Bacteria. Sensors (2022) 22(22), 8606

63. J. Klüpfel, S. Paßreiter, M. Rumpf, C. Christa, H.-P. Holthoff, M. Ungerer, M. Lohse, P. Knolle, U. Protzer, M. Elsner, M. Seidel. Automated detection of neutralizing SARS-CoV-2 antibodies in minutes using a competitive chemiluminescence immunoassay. Analytical and Bioanalytical Chemistry (2022),

62. J. Klüpfel, S. Paßreiter, N. Weidlein, M. Knopp, M. Ungerer, U. Protzer, P. Knolle, O. Hayden, M. Elsner, M. Seidel, Fully automated chemiluminescence microarray analysis platform for rapid and multiplexed SARS-CoV-2 serodiagnostics. Anal. Chem. 94 (2022), pp. 2855–2864, DOI: 10.1021/acs.analchem.1c04672

61. Wang, Y.; Rink, S.; Baeumner, A.J.; Seidel, M.; Microfluidic flow-injection aptamer-based chemiluminescence platform for sulfadimethoxine detection. Microchimica Acta, 2022, 189, 117.

60. Rink, S.; Duerkop, A.; von Wangelin, A.J.; Seidel, M; Baeumner, A.J. Next generation luminol derivative as powerful benchmark probe for chemiluminescence assays. Analytica Chimica Acta, 2021, 1188, 339161

59. Wang, Y.; Seidel, M. Integration of 3D hydrodynamic focused microreactor with microfluidic chemiluminescence sensing for online synthesis and catalytical characterization of gold nanoparticles. Sensors, 2021, 21 (7), 2290.

58. Wang, Y.; Seidel, M. Strategy for fast manufacturing of 3D hydrodynamic focusing multilayer microfluidic chips and its application for flow-based synthesis of gold nanoparticles. Microfluidics and Nanofluidics, 2021,

57. Klüpfel, J.; Würstle, S.; Seidel, M.; Elsner, M. Automated, flow-based chemiluminescence microarray immunoassay for the rapid multiplex detection of IgG antibodies to SARS-CoV-2 in human serum and plasma (CoVRapid CL-MIA). Analytical and Bioanalytical Chemsitry, 2021,

56. Hess, S.; Niessner, R., Seidel, M. Quantitative detection of human adenovirus from river water by monolithic adsorption filtration and quantitative PCR. Journal of Virological Methods, 2021, 292, 114128.

55. Sollweck, K.; Streich, P.; Elsner M.; Seidel, M. A chip-based colony fusion recombinase polymerase amplification assay for monitoring of antimicrobial resistance genes and their carrying species in surface water. ACS ES&T Water, 2021,

54. Sollweck, K.; Schwaiger, G.; Seidel, M. A chemiluminescence-based heterogeneous asymmetric recombinase polymerase amplification assay for the molecular detection of mycotoxin producers. Analyst, 2021, 1074-1083.

53. Göpfert, L.; Elsner, M.; Seidel, M. Isothermal haRPA detection of bla CTX-M in bacterial isolates from water samples and comparison with qPCR. Analytical Methods, 2021 13 (4), 552-557. DOI: 10.1039/d0ay02000a.

52. Göpfert, L.; Klüpfel, J.; Heinritz, C.; Elsner, M.; Seidel, M. Macroporous epoxy-based monoliths for rapid quantification of Pseudomonas aeruginosa by adsorption elution method optimized for qPCR. Analytical and Bioanalytical Chemistry, 2020, 412, 8185–8195.

51. Meyer, V.K.; Chatelle, C.V.; Weber, W.; Niessner, R.; Seidel, M. Flow-based regenerable chemiluminescence receptor assay for the detection of tetracyclines. Analytical and Bioanalytical Chemistry, 2020,

50. Walser-Reichenbach, S.M.; Zamfir, M.; Seidel, M.; Lueck, C.; Heinze, S.;  Herr, C.E.W. Guideline VDI 4259 Part 1" Catalog of Measures in Case of suspected emission-related legionellosis Outbreaks Identification and Investigation of Aerosol-emitting Environmental Sources in the Context of Legionellosis Outbreaks. Gefahrstoffe Reinhaltung der Luft, 2019, 79, 334-335.

49. Nistler, A.; Niessner, R., Seidel, M. Magnetic nanocomposites: versatile tool for the combination of immunomagnetic separation with flow-based chemiluminescence immunochip for rapid biosensing of staphylococcal enterotoxin B in milk. Analytical and Bioanalytical Chemistry, 2019, 411(19):4951-4961. DOI: 10.1007/s00216-019-01808-z.

48. Bemetz, J.; Kober, C.; Meyer, V.; Niessner, R.; Seidel, M. Succinylated Jeffamine ED-2003 coated polycarbonate chips for low-cost analytical microarrays. Analytical and Bioanalytical Chemistry, 2019, 411, 1943–1955. DOI: 10.1007/s00216-019-01594-8.

47. Weiss, R.; Palatinszky, M.; Wagner, M.; Niessner, R.; Elsner, M.; Seidel, M.; Ivleva, N. Surface-enhanced Raman spectroscopy of microorganisms: limitations and applicability on the single-cell level. The Analyst, 2019, 144, 943-953. DOI: 10.1039/C8AN02177E.

46. Bemetz, J.; Wegemann, A.;  Saatchi, K.; Haase, A.;  Häfeli, U.O.; Niessner, R.; Gleich, B.; Seidel, M. Microfluidic-Based Synthesis of Magnetic Nanoparticles Coupled with Miniaturized NMR for Online Relaxation Studies. Analytical Chemistry, 2018, 90, 16, 9975-9982. DOI:10.1021/acs.analchem.8b02374.

45. Elsäßer, D.; Ho, H.; Niessner, R.; Tiehm, A.; Seidel, M. Heterogeneous asymmetric recombinase polymerase amplification (haRPA) for rapid hygiene control of large-volume water samples.  Analytical Biochemistry, 2018, 546, 58-64.

44. Kober, C.; Niessner, R.; Seidel, M. Quantification of viable and non-viable Legionella spp. by heterogeneous asymmetric recombinase polymerase amplification (haRPA) on a flow-based chemiluminescence microarray. Biosensors and Bioelectronics, 2018, 100, 49-55.

43. Nistler, A.; Hartmann, C.; Rümenapp, C.; Opel, M.; Gleich, B.; Niessner, R.; Seidel, M.; Production and characterization of long-term stable superparamagnetic iron oxide-shell silica-core nanocomposites. Journal of Magnetism and Magnetic Materials, 2017, 442, 497-503.

42. Hjelmsø, M.H.; Hellmér, M.; Fernandez-Cassi, X.; Timoneda, N; Lukjancenko, O.; Seidel, M.; Elsässer, D.; Aarestrup, F.M.; Löfström, C.; Bofill-Mas, S.; Abril, J.A.; Girones, R.; Schultz, A.C. Evaluation of Methods for the Concentration and Extraction of viruses from Sewage in the Context of Metagenomic Sequencing. PLOS ONE, 2017, 1, e0170199. DOI:10.1371/journal.pone.0170199.

41. Meyer, V.K.; Meloni, D.; Olivo, F.; Märtlbauer, E.; Dietrich, R.; Niessner, R.; Seidel, M. Validation procedure for multiplex antibiotic immunoassays using flow-based chemiluminescence microarrays. In: M. Uttamchandani & S.Q. Yao, Small Molecule Microarrays: Methods and Protocols of the series Methods in Molecular Biology, 2017, Volume 1518, 195-212. DOI: 10.1007/978-1-4939-6584-7_13.

40. Walser, S.M.; Brenner, B., Wunderlich, A.; Tuschak, C.; Huber, S.; Kolb, S.; Niessner, R.; Seidel, M.; Höller, C.; Herr, C.E.W. Detection of Legionella-contaminated aerosols in the vicinity of a bio-trickling filter of a breeding sow facility–A pilot study. Science of The Total Environment, 2017, 575, 1197-1202. DOI:10.1016/j.scitotenv.2016.09.191.

39. Karthe, D.; Behrmann, O.; Blättel, V.; Elsässer, D.; Heese, C.; Hügle, M.; Hufert, F.; Kunze, A.; Niessner, R.; Ho, J.; Scharaw, B.; Spoo, M.; Tiehm, A.; Urban, G.; Vosseler, S.; Westerhoff, T.; Dame, G.; Seidel, M. Modular development of an inline monitoring system for waterborne pathogens in raw and drinking water. Environmental Earth Sciences 2016, 75, 1481. DOI: 10.1007/s12665-016-6287-9.

38. Seidel, M.; Jurzik, L.; Brettar, I.; Hoefle, M.;  Griebler, C. Microbial and viral pathogens in freshwater—current research aspects studied in Germany. Environmental Earth Science, 2016, 75, 1384. DOI:10.1007/s12665-016-6189-x.

37. Kiwull, B.; Wunderlich, A.; Herr, C.E.W.; Niessner, R.; Seidel, M. Bioaerosol chamber for Legionella containing shower aerosols, Gefahrstoffe - Reinhaltung der Luft, 2016, 76(9), 344-350.

36. Ho, J.; Seidel, M.; Niessner, R.; Eggers, J.; Tiehm, A., Long amplicon (LA)-qPCR for the discrimination of infectious and noninfectious phix 174. Water Research, 2016, 103, 141-148. doi:10.1016/j.watres.2016.07.032.

35. Wunderlich, A.; Torggler, C.; Elsaesser, D.; Lück, C.; Niessner, R.; Seidel, M., Rapid quantification method for Legionella pneumophila in surface water. Analytical and Bioanalytical Chemistry, 2016, 408(9), 2203-2213. DOI: 10.1007/s00216-016-9362-x.

34. Kunze, A.; Dilcher, M.; Abd El Wahed, A.; Hufert, F.; Niessner, R. and Seidel, M., On-Chip Isothermal Nucleic Acid Amplification on Flow-Based Chemiluminescence Microarray Analysis Platform for the Detection of Viruses and Bacteria. Analytical Chemistry, 2016, 88, 898–905. DOI:10.1021/acs.analchem.5b03540.

33. Kunze, A.; Pei, L.; Elsaesser, D.; Niessner, R.; Seidel, M., High performance concentration method for viruses in drinking water. Journal of Virological Methods, 2015, 222, 132-137; DOI: 10.1016/j.jviromet.2015.06.007

32. Meyer, V.K.; Kober, C.; Niessner, R.; Seidel, M., Regeneration of Recombinant Antigen Microarrays for the Automated Monitoring of Antibodies against Zoonotic Pathogens in Swine Sera. Sensors, 2015, 15, 2614-2628. DOI: 10.3390/s150202614

31. Szkola, A.; Linares E.M.; Worbs, S.; Dorner, B.G.; Dietrich, R.; Märtlbauer, E.; Niessner, R.; Seidel, M., Rapid and simultaneous detection of ricin, staphylococcal enterotoxin B and saxitoxin by chemiluminescence-based microarray immunoassay. The Analyst, 2014, 139, 5886-5893, DOI: 10.1039/c4an00345d.

30. Seidel, M. and Niessner, R., Chemiluminescence microarrays: a critical review. Analytical and Bioanalytical Chemistry, 2014,406, 5589–5612,

29. Lengger, S.; Otto, J.; Elsaesser, D.; Schneider, O.; Tiehm, A.; Fleischer, J.; Niessner, R.; Seidel, M., Oligonucleotide microarray chip for the quantification of MS2, PhiX174, and adenoviruses on the multiplex analysis platform MCR 3. Analytical Bioanalytical Chemistry, 2014

, 406, 3323-3334,

28. Szkola, A.; Campbell, K.; Elliott, C.P.; Niessner, R.; Seidel, M., Automated, high performance, flow-through chemiluminescence microarray for the multiplexed detection of phycotoxins. Analytica Chimica Acta, 2013

, 797, 211-218,

27. Wutz, K.; Meyer, V.K.; Wachek, S.; Krol, P.; Gareis, M.; Nölting, C.; Struck, F.; Soutschek, E.; Böcher, O.; Niessner, R.; Seidel, M., New route for fast detection of antibodies against zoonotic pathogens in sera of slaughtered pigs by means of flow-through chemiluminescence immunochips. Analytical Chemistry, 2013, 85, 5279-5285.

26. Huebner, M.; Wutz, K.; Szkola A.; Niessner, R.; Seidel, M., A Glyco-chip for the Detection of Ricin by an Automated Chemiluminescence Read-out System. Analytical Sciences, 2013, 29(4), 461-466.

25.  Lengger, S.; Niessner, R.; Seidel, M., Pathogens in Water - enrich and verify. Nachrichten aus der Chemie, 2012, 60, 1208-1212.

24. Pei, L.; Rieger, M.; Lengger, S.; Ott, S.; Zawadsky, C.; Hartmann, N.M.; Selinka, H.C.; Tiehm, A., Niessner, R., Seidel, M., Combination of crossflow ultrafiltration, monolithic affinity filtration, and quantitative reverse transcriptase PCR for rapid concentration and quantification of model viruses in water. Environmental Science & Technology, 2012, 46, 10073-10080.

23. Rieger, M.; Schaumann, G.E.; Mouvenchery, Y.K.; Niessner, R.; Seidel, M.; Baumann, T., Development of antibody-labelled superparamagnetic nanoparticles for the visualisation of benzo[a]pyrene in porous media with magnetic resonance imaging. Analytical and Bioanalytical Chemistry, 2012, 403, 2529-2540.

22. Langer, V.; Hartmann, G.; Niessner, R.; Seidel, M., Rapid quantification of bioaerosols containing L. pneumophila by Coriolis µ air sampler and chemiluminescence antibody microarrays. Journal of Aerosol Science, 2012, 48, 46-55.

21. Ott, S.; Niessner, R.; Seidel, M., Preparation of epoxy-based macroporous monolithic columns for the efficient immunofiltration of Staphylococcus aureus. Journal of Separation Science, 2011, 34, 2181-2192.

20. Ali, Z.; Abbasi, A. Z.; Zhang, F.; Arosio, P; Lascialfari, A.; Casula, M. F.; Wenk, A.; Kreyling, W.; Plapperer, R.; Seidel, M.; Niessner, R.; Knoell, J.; Seubert, A.; Parak, W. J., Multifunctional Nanoparticles for Dual Imaging. Analytical Chemistry, 2011, 83, 2877-2882.

19. Donhauser, S.C.; Niessner, R.; Seidel, M., Sensitive quantification of Escherichia coli O157:H7, Salmonella enterica, and Campylobacter jejuni by combining stopped polymerase chain reaction with chemiluminescence flow-through DNA microarray analysis. Analytical Chemistry, 2011, 83, 3153-3560.

18. Wutz, K.; Niessner, R.; Seidel, M., Simultaneous determination of four different antibiotic residues in honey by chemiluminescence multianalyte chip immunoassays. Microchimica Acta, 2011, 173, 1-9.

17. Langer, V.; Niessner, R.; Seidel, M., Stopped-flow microarray immunoassay for the detection of viable E. coli by use of chemiluminescence flow-through microarrays. Analytical and Bioanalytical Chemistry, 2011, 399, 1041-1050. 

16. Botzenhart, K.; Seidel, M., Wasservirologie, In: R. Niessner, Höll - Wasser 2010, 412-426, deGruyter, Berlin.

15. Carlson, S.; Seidel, M., Mikrobiologie des Wassers, In: R. Niessner, Höll - Wasser 2010, 305-409, deGruyter, Berlin.

14. Seidel, M.; Niessner, R., Chemiluminescene to Immunoassays. In: A. Roda, Chemiluminescence and Bioluminescence 2010, RSC, Cambridge.

13. Pappert, G.; Rieger, M.; Niessner, R., Seidel, M., Immunomagnetic nanoparticle-based sandwich chemiluminescence-ELISA for the enrichment and quantification of E. coli. Microchimica Acta, 2010, 168, 1-8.

12. Karsunke, X.Y.Z.; Niessner R.; Seidel, M., Development of a multichannel flow-through chemiluminescence microarray chip for parallel calibration and detection of pathogenic bacteria. Analytical and Bioanalytical Chemistry, 2009, 395, 1623-1630.

11. Kloth, K.; Rye-Johnsen, M.; Didier, A.; Dietrich, R.; Märtlbauer E.; Niessner, R.; Seidel, M., A regenerable immunochip for the rapid determination of 13 different antibiotics in raw milk. The Analyst, 2009, 134, 1433 - 1439.

10. Donhauser, S.C.; Niessner R.; Seidel, M., Quantification of E. coli DNA on a flow-through chemiluminescence microarray read-out system after PCR Amplification. Analytical Sciences, 2009, 25, 669-674.

9. Peskoller, C.; Niessner, R.; Seidel, M., Development of an epoxy-based monolith used for the affinity capturing of Escherichia coli bacteria. Journal of Chromatography A, 2009, 1216, 3794-3801.

8. Kloth, K.; Niessner, R.; Seidel M., An open stand-alone platform for regenerable automated microarrays. Biosensors & Bioelectronics, 2009, 24, 2106-2112.

7. Peskoller, C.; Niessner, R.; Seidel, M., Cross-flow microfiltration system for rapid enrichment of bacteria in water. Analytical and Bioanalytical Chemistry, 2009, 393, 399-404.

6. Seidel, M.; Niessner, R., Analytical microarrays: a critical review. Analytical and Bioanalytical Chemistry, 2008, 391, 1521-1544.

5. Wolter, A.; Niessner, R.; Seidel M., Detection of Escherichia coli O157:H7, Salmonella typhimurium, and Legionella pneumophila in water using a flow-through chemiluminescence microarray readout system. Analytical Chemistry, 2008, 80, 5854-5863.

4. Wolter, A.; Niessner, R.; Seidel M., Preparation and characterization of functional poly(ethylene glycol) surfaces for the use of antibody microarrays. Analytical Chemistry, 2007, 79, 4529-4537.

3. Seidel, M.; Dankbar, D.M.; Gauglitz, G., A miniaturized heterogeneous fluorescence immunoassay on gold-coated nanotiter plates. Analytical and Bioanalytical Chemistry, 2004, 379, 904-912.

2. Kröger, K.; Seidel, M.; Gauglitz, G., Optical sensing methods in high-throughput screening. In: High-Throughput Analysis: A Tool for Combinatorial Material Science. Edited by R.A. Potyrailo, Kluwer Academic, New York, 2003, p. 261-288.

1. Seidel, M.; Gauglitz, G. Miniaturization and parallelization of fluorescence immunoassays in nanotiter plates. TrAC, Trends in Analytical Chemistry 2003, 22, 385-394.

Group of Bioanalytics and Microanalytical Systems - PD Dr. Michael Seidel