Publications

67. J. Neumair, M. Kröger, E. Stütz, C. Jerin, A. M. Chaker, C. B. Schmidt-Weber and Seidel, M. Flow-Based CL-SMIA for the Quantification of Protein Biomarkers from Nasal Secretions in Comparison with Sandwich ELISA. Biosensors, 2023, 13(7), 670, https://www.mdpi.com/2079-6374/13/7/670

66. Heining, L.; Welp, L.; Hugo, A; Elsner, M.; Seidel, M. Immunomagnetic separation coupled with flow cytometry for the analysis of Legionella pneumophila in aerosols. Analytical Bioanalytical Chemistry, 2023, 1-11, https://doi.org/10.1007/s00216-023-04738-z.

65. Neumair, J.; D’Ercole; De March, M.; Elsner, M.; Seidel, M.; De Marco, A. Macroporous epoxy-based monoliths functionalized with anti-CD63 nanobodies for effective isolation of extracellular vesicles in urine. International Journal of Molecular Sciences, 2023, 24, 6131, https://doi.org/10.3390/ijms24076131

64. J.Neumair, M. Elsner and Seidel, M. Flow-Based Chemiluminescence Microarrays as Screening Platform for Affinity Binders to Capture and Elute Bacteria. Sensors 2023, 22(22), 8606, https://doi.org/10.3390/s22228606

63. J. Klüpfel, S. Paßreiter, M. Rumpf, C. Christa, H.-P. Holthoff, M. Ungerer, M. Lohse, P. Knolle, U. Protzer, M. Elsner, Seidel M. Automated detection of neutralizing SARS-CoV-2 antibodies in minutes using a competitive chemiluminescence immunoassay. Analytical and Bioanalytical Chemistry, 2023, 415, 391-404, doi.org/10.1007/s00216-022-04416-6

62. J. Klüpfel, S. Paßreiter, N. Weidlein, M. Knopp, M. Ungerer, U. Protzer, P. Knolle, O. Hayden, M. Elsner, Seidel M. Fully automated chemiluminescence microarray analysis platform for rapid and multiplexed SARS-CoV-2 serodiagnostics. Analytical Chemistry, 2022, 94, 2855–2864, DOI: 10.1021/acs.analchem.1c04672

61. Wang, Y.; Rink, S.; Baeumner, A.J.; Seidel, M.; Microfluidic flow-injection aptamer-based chemiluminescence platform for sulfadimethoxine detection. Microchimica Acta, 2022, 189, 117. doi.org/10.10/s00604-022-05216-6.

60. Rink, S.; Duerkop, A.; von Wangelin, A.J.; Seidel, M; Baeumner, A.J. Next generation luminol derivative as powerful benchmark probe for chemiluminescence assays. Analytica Chimica Acta, 2021, 1188, 339161

59. Wang, Y.; Seidel, M. Integration of 3D hydrodynamic focused microreactor with microfluidic chemiluminescence sensing for online synthesis and catalytical characterization of gold nanoparticles. Sensors, 2021, 21 (7), 2290.

58. Wang, Y.; Seidel, M. Strategy for fast manufacturing of 3D hydrodynamic focusing multilayer microfluidic chips and its application for flow-based synthesis of gold nanoparticles. Microfluidics and Nanofluidics, 2021, https://link.springer.com/article/10.1007/s10404-021-02463-6

57. Klüpfel, J.; Würstle, S.; Seidel, M.; Elsner, M. Automated, flow-based chemiluminescence microarray immunoassay for the rapid multiplex detection of IgG antibodies to SARS-CoV-2 in human serum and plasma (CoVRapid CL-MIA). Analytical and Bioanalytical Chemsitry, 2021, 413, 5619-5632, https://link.springer.com/article/10.1007/s00216-021-03315-6

56. Hess, S.; Niessner, R., Seidel, M. Quantitative detection of human adenovirus from river water by monolithic adsorption filtration and quantitative PCR. Journal of Virological Methods, 2021, 292, 114128.
https://doi.org/10.1016/j.jviromet.2021.114128

55. Sollweck, K.; Streich, P.; Elsner M.; Seidel, M. A chip-based colony fusion recombinase polymerase amplification assay for monitoring of antimicrobial resistance genes and their carrying species in surface water. ACS ES&T Water, 2021, https://doi.org/10.1021/acsestwater.0c00110.

54. Sollweck, K.; Schwaiger, G.; Seidel, M. A chemiluminescence-based heterogeneous asymmetric recombinase polymerase amplification assay for the molecular detection of mycotoxin producers. Analyst, 2021, 1074-1083. https://doi.org/10.1039/D0AN02000A

53. Göpfert, L.; Elsner, M.; Seidel, M. Isothermal haRPA detection of bla CTX-M in bacterial isolates from water samples and comparison with qPCR. Analytical Methods, 2021 13 (4), 552-557. DOI: 10.1039/d0ay02000a.

52. Göpfert, L.; Klüpfel, J.; Heinritz, C.; Elsner, M.; Seidel, M. Macroporous epoxy-based monoliths for rapid quantification of Pseudomonas aeruginosa by adsorption elution method optimized for qPCR. Analytical and Bioanalytical Chemistry, 2020, 412, 8185–8195. https://doi.org/10.1007/s00216-020-02956-3

51. Meyer, V.K.; Chatelle, C.V.; Weber, W.; Niessner, R.; Seidel, M. Flow-based regenerable chemiluminescence receptor assay for the detection of tetracyclines. Analytical and Bioanalytical Chemistry, 2020, http://link.springer.com/article/10.1007/s00216-019-02368-y

50. Walser-Reichenbach, S.M.; Zamfir, M.; Seidel, M.; Lueck, C.; Heinze, S.;  Herr, C.E.W. Guideline VDI 4259 Part 1" Catalog of Measures in Case of suspected emission-related legionellosis Outbreaks Identification and Investigation of Aerosol-emitting Environmental Sources in the Context of Legionellosis Outbreaks. Gefahrstoffe Reinhaltung der Luft, 2019, 79, 334-335.

49. Nistler, A.; Niessner, R., Seidel, M. Magnetic nanocomposites: versatile tool for the combination of immunomagnetic separation with flow-based chemiluminescence immunochip for rapid biosensing of staphylococcal enterotoxin B in milk. Analytical and Bioanalytical Chemistry, 2019, 411(19):4951-4961. DOI: 10.1007/s00216-019-01808-z.

48. Bemetz, J.; Kober, C.; Meyer, V.; Niessner, R.; Seidel, M. Succinylated Jeffamine ED-2003 coated polycarbonate chips for low-cost analytical microarrays. Analytical and Bioanalytical Chemistry, 2019, 411, 1943–1955. DOI: 10.1007/s00216-019-01594-8.

47. Weiss, R.; Palatinszky, M.; Wagner, M.; Niessner, R.; Elsner, M.; Seidel, M.; Ivleva, N. Surface-enhanced Raman spectroscopy of microorganisms: limitations and applicability on the single-cell level. The Analyst, 2019, 144, 943-953. DOI: 10.1039/C8AN02177E.

46. Bemetz, J.; Wegemann, A.;  Saatchi, K.; Haase, A.;  Häfeli, U.O.; Niessner, R.; Gleich, B.; Seidel, M. Microfluidic-Based Synthesis of Magnetic Nanoparticles Coupled with Miniaturized NMR for Online Relaxation Studies. Analytical Chemistry, 2018, 90, 16, 9975-9982. DOI:10.1021/acs.analchem.8b02374.

45. Elsäßer, D.; Ho, H.; Niessner, R.; Tiehm, A.; Seidel, M. Heterogeneous asymmetric recombinase polymerase amplification (haRPA) for rapid hygiene control of large-volume water samples.  Analytical Biochemistry, 2018, 546, 58-64. https://doi.org/10.1016/j.ab.2018.01.032.

44. Kober, C.; Niessner, R.; Seidel, M. Quantification of viable and non-viable Legionella spp. by heterogeneous asymmetric recombinase polymerase amplification (haRPA) on a flow-based chemiluminescence microarray. Biosensors and Bioelectronics, 2018, 100, 49-55. https://doi.org/10.1016/j.bios.2017.08.053.

43. Nistler, A.; Hartmann, C.; Rümenapp, C.; Opel, M.; Gleich, B.; Niessner, R.; Seidel, M.; Production and characterization of long-term stable superparamagnetic iron oxide-shell silica-core nanocomposites. Journal of Magnetism and Magnetic Materials, 2017, 442, 497-503. https://doi.org/10.1016/j.jmmm.2017.07.005

42. Hjelmsø, M.H.; Hellmér, M.; Fernandez-Cassi, X.; Timoneda, N; Lukjancenko, O.; Seidel, M.; Elsässer, D.; Aarestrup, F.M.; Löfström, C.; Bofill-Mas, S.; Abril, J.A.; Girones, R.; Schultz, A.C. Evaluation of Methods for the Concentration and Extraction of viruses from Sewage in the Context of Metagenomic Sequencing. PLOS ONE, 2017, 1, e0170199. DOI:10.1371/journal.pone.0170199.

41. Meyer, V.K.; Meloni, D.; Olivo, F.; Märtlbauer, E.; Dietrich, R.; Niessner, R.; Seidel, M. Validation procedure for multiplex antibiotic immunoassays using flow-based chemiluminescence microarrays. In: M. Uttamchandani & S.Q. Yao, Small Molecule Microarrays: Methods and Protocols of the series Methods in Molecular Biology, 2017, Volume 1518, 195-212. DOI: 10.1007/978-1-4939-6584-7_13.

40. Walser, S.M.; Brenner, B., Wunderlich, A.; Tuschak, C.; Huber, S.; Kolb, S.; Niessner, R.; Seidel, M.; Höller, C.; Herr, C.E.W. Detection of Legionella-contaminated aerosols in the vicinity of a bio-trickling filter of a breeding sow facility–A pilot study. Science of The Total Environment, 2017, 575, 1197-1202. DOI:10.1016/j.scitotenv.2016.09.191.

39. Karthe, D.; Behrmann, O.; Blättel, V.; Elsässer, D.; Heese, C.; Hügle, M.; Hufert, F.; Kunze, A.; Niessner, R.; Ho, J.; Scharaw, B.; Spoo, M.; Tiehm, A.; Urban, G.; Vosseler, S.; Westerhoff, T.; Dame, G.; Seidel, M. Modular development of an inline monitoring system for waterborne pathogens in raw and drinking water. Environmental Earth Sciences 2016, 75, 1481. DOI: 10.1007/s12665-016-6287-9.

38. Seidel, M.; Jurzik, L.; Brettar, I.; Hoefle, M.;  Griebler, C. Microbial and viral pathogens in freshwater—current research aspects studied in Germany. Environmental Earth Science, 2016, 75, 1384. DOI:10.1007/s12665-016-6189-x. http://rdcu.be/lEKX

37. Kiwull, B.; Wunderlich, A.; Herr, C.E.W.; Niessner, R.; Seidel, M. Bioaerosol chamber for Legionella containing shower aerosols, Gefahrstoffe - Reinhaltung der Luft, 2016, 76(9), 344-350.

36. Ho, J.; Seidel, M.; Niessner, R.; Eggers, J.; Tiehm, A., Long amplicon (LA)-qPCR for the discrimination of infectious and noninfectious phix 174. Water Research, 2016, 103, 141-148. doi:10.1016/j.watres.2016.07.032.

35. Wunderlich, A.; Torggler, C.; Elsaesser, D.; Lück, C.; Niessner, R.; Seidel, M., Rapid quantification method for Legionella pneumophila in surface water. Analytical and Bioanalytical Chemistry, 2016, 408(9), 2203-2213. DOI: 10.1007/s00216-016-9362-x.

34. Kunze, A.; Dilcher, M.; Abd El Wahed, A.; Hufert, F.; Niessner, R. and Seidel, M., On-Chip Isothermal Nucleic Acid Amplification on Flow-Based Chemiluminescence Microarray Analysis Platform for the Detection of Viruses and Bacteria. Analytical Chemistry, 2016, 88, 898–905. DOI:10.1021/acs.analchem.5b03540.

33. Kunze, A.; Pei, L.; Elsaesser, D.; Niessner, R.; Seidel, M., High performance concentration method for viruses in drinking water. Journal of Virological Methods, 2015, 222, 132-137; DOI: 10.1016/j.jviromet.2015.06.007

32. Meyer, V.K.; Kober, C.; Niessner, R.; Seidel, M., Regeneration of Recombinant Antigen Microarrays for the Automated Monitoring of Antibodies against Zoonotic Pathogens in Swine Sera. Sensors, 2015, 15, 2614-2628. DOI: 10.3390/s150202614

31. Szkola, A.; Linares E.M.; Worbs, S.; Dorner, B.G.; Dietrich, R.; Märtlbauer, E.; Niessner, R.; Seidel, M., Rapid and simultaneous detection of ricin, staphylococcal enterotoxin B and saxitoxin by chemiluminescence-based microarray immunoassay. The Analyst, 2014, 139, 5886-5893, DOI: 10.1039/c4an00345d.

30. Seidel, M. and Niessner, R., Chemiluminescence microarrays: a critical review. Analytical and Bioanalytical Chemistry, 2014,406, 5589–5612, http://link.springer.com/article/10.1007/s00216-014-7968-4.

29. Lengger, S.; Otto, J.; Elsaesser, D.; Schneider, O.; Tiehm, A.; Fleischer, J.; Niessner, R.; Seidel, M., Oligonucleotide microarray chip for the quantification of MS2, PhiX174, and adenoviruses on the multiplex analysis platform MCR 3. Analytical Bioanalytical Chemistry, 2014

, 406, 3323-3334, link.springer.com/article/10.1007%2Fs00216-014-7641-y.

28. Szkola, A.; Campbell, K.; Elliott, C.P.; Niessner, R.; Seidel, M., Automated, high performance, flow-through chemiluminescence microarray for the multiplexed detection of phycotoxins. Analytica Chimica Acta, 2013

, 797, 211-218, dx.doi.org/10.1016/j.aca.2013.05.028.

27. Wutz, K.; Meyer, V.K.; Wachek, S.; Krol, P.; Gareis, M.; Nölting, C.; Struck, F.; Soutschek, E.; Böcher, O.; Niessner, R.; Seidel, M., New route for fast detection of antibodies against zoonotic pathogens in sera of slaughtered pigs by means of flow-through chemiluminescence immunochips. Analytical Chemistry, 2013, 85, 5279-5285.

26. Huebner, M.; Wutz, K.; Szkola A.; Niessner, R.; Seidel, M., A Glyco-chip for the Detection of Ricin by an Automated Chemiluminescence Read-out System. Analytical Sciences, 2013, 29(4), 461-466.

25.  Lengger, S.; Niessner, R.; Seidel, M., Pathogens in Water - enrich and verify. Nachrichten aus der Chemie, 2012, 60, 1208-1212.

24. Pei, L.; Rieger, M.; Lengger, S.; Ott, S.; Zawadsky, C.; Hartmann, N.M.; Selinka, H.C.; Tiehm, A., Niessner, R., Seidel, M., Combination of crossflow ultrafiltration, monolithic affinity filtration, and quantitative reverse transcriptase PCR for rapid concentration and quantification of model viruses in water. Environmental Science & Technology, 2012, 46, 10073-10080.

23. Rieger, M.; Schaumann, G.E.; Mouvenchery, Y.K.; Niessner, R.; Seidel, M.; Baumann, T., Development of antibody-labelled superparamagnetic nanoparticles for the visualisation of benzo[a]pyrene in porous media with magnetic resonance imaging. Analytical and Bioanalytical Chemistry, 2012, 403, 2529-2540.

22. Langer, V.; Hartmann, G.; Niessner, R.; Seidel, M., Rapid quantification of bioaerosols containing L. pneumophila by Coriolis µ air sampler and chemiluminescence antibody microarrays. Journal of Aerosol Science, 2012, 48, 46-55.

21. Ott, S.; Niessner, R.; Seidel, M., Preparation of epoxy-based macroporous monolithic columns for the efficient immunofiltration of Staphylococcus aureus. Journal of Separation Science, 2011, 34, 2181-2192.

20. Ali, Z.; Abbasi, A. Z.; Zhang, F.; Arosio, P; Lascialfari, A.; Casula, M. F.; Wenk, A.; Kreyling, W.; Plapperer, R.; Seidel, M.; Niessner, R.; Knoell, J.; Seubert, A.; Parak, W. J., Multifunctional Nanoparticles for Dual Imaging. Analytical Chemistry, 2011, 83, 2877-2882.

19. Donhauser, S.C.; Niessner, R.; Seidel, M., Sensitive quantification of Escherichia coli O157:H7, Salmonella enterica, and Campylobacter jejuni by combining stopped polymerase chain reaction with chemiluminescence flow-through DNA microarray analysis. Analytical Chemistry, 2011, 83, 3153-3560.

18. Wutz, K.; Niessner, R.; Seidel, M., Simultaneous determination of four different antibiotic residues in honey by chemiluminescence multianalyte chip immunoassays. Microchimica Acta, 2011, 173, 1-9.

17. Langer, V.; Niessner, R.; Seidel, M., Stopped-flow microarray immunoassay for the detection of viable E. coli by use of chemiluminescence flow-through microarrays. Analytical and Bioanalytical Chemistry, 2011, 399, 1041-1050. 

16. Botzenhart, K.; Seidel, M., Wasservirologie, In: R. Niessner, Höll - Wasser 2010, 412-426, deGruyter, Berlin.

15. Carlson, S.; Seidel, M., Mikrobiologie des Wassers, In: R. Niessner, Höll - Wasser 2010, 305-409, deGruyter, Berlin.

14. Seidel, M.; Niessner, R., Chemiluminescene to Immunoassays. In: A. Roda, Chemiluminescence and Bioluminescence 2010, RSC, Cambridge.

13. Pappert, G.; Rieger, M.; Niessner, R., Seidel, M., Immunomagnetic nanoparticle-based sandwich chemiluminescence-ELISA for the enrichment and quantification of E. coli. Microchimica Acta, 2010, 168, 1-8.

12. Karsunke, X.Y.Z.; Niessner R.; Seidel, M., Development of a multichannel flow-through chemiluminescence microarray chip for parallel calibration and detection of pathogenic bacteria. Analytical and Bioanalytical Chemistry, 2009, 395, 1623-1630.

11. Kloth, K.; Rye-Johnsen, M.; Didier, A.; Dietrich, R.; Märtlbauer E.; Niessner, R.; Seidel, M., A regenerable immunochip for the rapid determination of 13 different antibiotics in raw milk. The Analyst, 2009, 134, 1433 - 1439.

10. Donhauser, S.C.; Niessner R.; Seidel, M., Quantification of E. coli DNA on a flow-through chemiluminescence microarray read-out system after PCR Amplification. Analytical Sciences, 2009, 25, 669-674.

9. Peskoller, C.; Niessner, R.; Seidel, M., Development of an epoxy-based monolith used for the affinity capturing of Escherichia coli bacteria. Journal of Chromatography A, 2009, 1216, 3794-3801.

8. Kloth, K.; Niessner, R.; Seidel M., An open stand-alone platform for regenerable automated microarrays. Biosensors & Bioelectronics, 2009, 24, 2106-2112.

7. Peskoller, C.; Niessner, R.; Seidel, M., Cross-flow microfiltration system for rapid enrichment of bacteria in water. Analytical and Bioanalytical Chemistry, 2009, 393, 399-404.

6. Seidel, M.; Niessner, R., Analytical microarrays: a critical review. Analytical and Bioanalytical Chemistry, 2008, 391, 1521-1544.

5. Wolter, A.; Niessner, R.; Seidel M., Detection of Escherichia coli O157:H7, Salmonella typhimurium, and Legionella pneumophila in water using a flow-through chemiluminescence microarray readout system. Analytical Chemistry, 2008, 80, 5854-5863.

4. Wolter, A.; Niessner, R.; Seidel M., Preparation and characterization of functional poly(ethylene glycol) surfaces for the use of antibody microarrays. Analytical Chemistry, 2007, 79, 4529-4537.

3. Seidel, M.; Dankbar, D.M.; Gauglitz, G., A miniaturized heterogeneous fluorescence immunoassay on gold-coated nanotiter plates. Analytical and Bioanalytical Chemistry, 2004, 379, 904-912.

2. Kröger, K.; Seidel, M.; Gauglitz, G., Optical sensing methods in high-throughput screening. In: High-Throughput Analysis: A Tool for Combinatorial Material Science. Edited by R.A. Potyrailo, Kluwer Academic, New York, 2003, p. 261-288.

1. Seidel, M.; Gauglitz, G. Miniaturization and parallelization of fluorescence immunoassays in nanotiter plates. TrAC, Trends in Analytical Chemistry 2003, 22, 385-394.

Group of Bioanalytics and Microanalytical Systems - PD Dr. Michael Seidel